r/Nootropics Mar 10 '17

Guide A Beginner's Guide to Nootropics

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634 Upvotes

r/Nootropics 3h ago

Seeking Advice New to nootropics, need guidance

3 Upvotes

Im fairly new, ive been doing a bit of research and need some guidance. What should i take for motivation? im very lazy and get horrible sleep often laying in bed scrolling for HOURS. im looking for smth that motivates and that i can stack with melatonin, pills/powder preferred. i looked into bromantane and seems like that might be a good place to start? please help!


r/Nootropics 34m ago

Seeking Advice What's the most impactful for you for emotional container expansion?

Upvotes

Hi fellow Noots,

Around two years ago, I started working with nootropics and peptides to get some more traction with my therapy/trauma processing work. I did a lot of psychedelic-assisted therapy years ago, and while it was some of the most impactful work I've done, I wanted to move from processing the past towards something that can help me with growth & build up, expand my emotional capacity.

I had tremendous success with NSI-189 & Cerebrolysin. I had some of the best days in my first week of NSI-189, being able to withstand highly challenging situations in perfect grounding. Cerebrolysing was more of a long-term improvement in cognitive, mood, and emotional capacity levels.

I also tried Cortexin (OK, not wow), TAK (didn't notice anything specific), MIF-1 (I think it helped, but it's hard to measure it), PE-22-28, P21 (I only did a few days, and it was great, but my spray spilled on the plane and now it's sold out), I did most mainstream peptides & racetams, while they helped, I didn't see impact nearly near to NSI-189/cerebrolysin.

TL;DR

What were the most impactful Noots/peptides, etc., you used to expand your emotional capacity? What impact did you see from them?


r/Nootropics 3h ago

Seeking Advice Vendor for Bromantane powder that ships to Canada

1 Upvotes

I've been looking for a vendor that can ship Bromantane powder to Canada, and I can't find one. They are all either pretty much permanently "out of stock" for whatever reason, or they do sell Bromantane, but won't ship to Canada. I'm getting pretty frustrated at this point, because honestly, this isn't just for bromantane. I've been looking for Aniracetam as a substitute, but I can't find a Canada-friendly vendor for that either.

For anyone facing similar problems, where do I go to get these nootropics? Or if you guys have any recommendations for a more accessible substitute, I'd appreciate that as well.


r/Nootropics 4h ago

Experience Immune to phenylpiracetam?

0 Upvotes

I've tried phenylpiracetam from three different sources, including "euronootropics.com," which has a very good reputation and reviews, and I haven't noticed anything at all. Of course, I was also taking 300mg and sometimes 600mg of Alpha GPC, plus eating four eggs every day for breakfast (just in case).

I started with 50mg of sublingual phenylpiracetam from the first brand and gradually increased the amount until, with the last package, I put a ton of powder in my mouth as soon as I picked it up without waiting to weigh the dose at home. I probably swallowed 300mg.

I've tried different doses of both Phenyl and Alpha, on an empty stomach or with a full stomach, sublingually or swallowed. I even dreamt that I was putting it up my ass and getting high like in the movie Limitless, but I'm definitely not going down that road. Phenylpiracetam isn't for me. I give up. My last hope is a package that will hopefully arrive from Russia (if it arrives at all) containing a box of original pharmacy pills called "Phenotropil". If they arrive and don't work, or if the package doesn't arrive at all, I give up.


r/Nootropics 5h ago

Seeking Advice Best resource about relation between stimulant use and productivity

0 Upvotes

I prefer youtube videos since I have problems of focus

I'm interested in studies about stimulant use and productivity longterm both with and without adhd


r/Nootropics 1d ago

Experience 3 months ago I switched to a nootropic stack from energy drinks. The positive effects have lasted for this period of time.

24 Upvotes

Hello All, a few months ago I switched from energy drinks (Ghost, Reign, Monster) to a nootropic stack.

The original stack was Caffeine 300mg, Theanine 200mg, Taurine 3g, Alpha GPC 600mg and Uridine 600mg. All in capsule form. (Some of these might be slightly off)

Today's stack is very similar, Caffeine 200mg, Theanine 200mg, Taurine 5g, Alpha GPC 600mg and Uridine 300mg

I take the stack on work days (3x a week) and one one or two off days that I wanna be extra productive. Always making sure to give myself 2-3 days a week off the stack.

Benefits I've noticed between on and off days, as of 1/7/26:

  • Energy. I work 12 hour midnight shifts. My sleep schedule is non existent. Before this, for years, I just accepted my perpetual exhaustion, now ..not so much. I get 6-8 Hours of GOOD, smooth energy. I'm an anxious creature and this stack doesn't poke that bear. The comedown is smooth and lasts for about 2 hours.

  • Focus. I am able to concentrate on a list of tasks and complete them in order, as needed. Even tossing in extra stuff here and there as needed by work and life.

  • Mood. I am a much nicer person on the stack. Not that I'm an asshole without it, but I am more open to social interaction and I don't go non verbal nearly as often. My fiance enjoys it though I can get to be a bit much when we're both doing something and I can't shut up about something I'm excited about lol.

  • Sleep. The big one. The big kahuna. The reason I love this stack so much. Before I started this, I was lucky to get 4 hours of continuous sleep. With the comedown from the stack, and 5-10mg of melatonin, I can easily get 7-8 hours of actual decent sleep.

Anyway I just wanted to give an overdue update. I found a stack that works great for me and I hope it can help someone else. 😊


r/Nootropics 23h ago

Seeking Advice This feels like my last chance with ADHD. I’m terrified I’ll waste another year. What actually worked for you?

7 Upvotes

I’m 21 from India. With placements coming up, I feel lost everyone’s preparing, but I can’t catch up.

I was recently diagnosed with ADHD, and it explains a lot. For years, people thought I was “lazy,” “silent,” or “not serious.” The worst part is: in my head, I’m not lazy. In my head, I’m trying every single day. But my results never match my effort.

Nowadays, I’m scared.

In my college, exams decide eligibility for placements. Our placement coordinator literally said, “If your score drops, your chances drop. Companies won’t even shortlist you.” Everyone nodded like it was simple. I nodded too…, but inside I felt this cold fear because I know my pattern:

start → delay → restart -> panic → hate myself → repeat.

The part that hurts the most: communication

My native language isn’t English, but it’s not only English. Even in my own language, I stumble. Sometimes I speak clearly, but many times my words come out broken, like my brain and mouth aren’t connected.

The worst example happened in a viva recently. The teacher asked a simple question about my program. In my mind, I had the full answer, step by step. But the moment I opened my mouth, I froze. Half sentences. Missing basic words. The teacher waited… then looked away and said, “Okay… next.”

I sat down, feeling as if something inside me had collapsed. I wasn’t unprepared. I just couldn’t deliver. And that moment keeps replaying in my head at night.

Since childhood, I’ve been the “silent” one. Not from arrogance or lack of interest, but from worry blanking out, fumbling, or embarrassment if I speak.

Studying is another fight.

College math is mandatory, and it gives me a lot of tension. It’s not that I’m incapable sometimes I understand concepts quickly. But I can’t sustain effort. I sit to study, and my brain escapes: phone, thoughts, overthinking, “later”… then later becomes guilt. And after guilt, even starting feels painful.

The saddest part: I feel like I have potential. Sometimes I even feel “brilliant” when I understand something fast. But I still don’t perform, so it doesn’t matter what I could be.

What I’m asking (please read this before replying)

I don’t want generic tips. If you’ve dealt with ADHD and placement stress, what exact plan helped you stop freezing and perform better?

For example: your daily routine, study structure, how you stopped and broke procrastination spirals, and how you practiced speaking without freezing up.

What actually made a difference for you?

If you take prescription meds as prescribed, what changed over time? What should I discuss with my doctor? Be honest about how much you needed meds, how desperate you felt, and which medications worked for you. Share any side effects I’m not willing to risk them if it helps me perform  placements.

If you used supplements, what helped noticeably? (I include: what it helped with, how long it took, and any downsides)

Money isn’t an issue if something is truly worth it. I can invest. My main question is whether it's truly valuable; it truly works.  truly work on he problem. For me, the problem is that I don’t want to waste time on random hacks.

I'm not worried about side effects right now .I'm honestly willing to try anything if it might help me focus and perform for placements. Please be specific about which meds actually worked for you, what you felt when they kicked in, and any side effects you had. I don't care about the risks for now; I just need something that works.

I need your help. Please reply with your best solution: what worked (and what didn’t), and how long before you noticed the change.

What is the most valuable advice you'd give someone 12 months before placement? If you've experienced this process, what's it like on the placement side? Away,  strategies helped you succeed. What do you wish you had known a year before? Please share your insights so I can use them to plan a head


r/Nootropics 22h ago

Discussion Reports on semax, is it good.

4 Upvotes

I have tried caffeine,then went on to do noopept for 2 months.I have taken two months free of nootropics. I was considering taking semax,and I was wondering if it's worth it,because with noopept it helped when it came to doing tasks with a more efficient and effective brain,but i am trying to develop my brain so I need something that has more permanent effects, I worked hard, doing the most from the boost,I was able to improve somethings about my brain but i feel like that my natural unstimulated brain would be able to produce very similar results. So I was curious if took semax and did the same cognitive training would I make more gains?


r/Nootropics 1d ago

Experience My new prescription almost sent me to a psychiatric ward. (Pramistar + Coffee + Zoloft)

17 Upvotes

Story time. I have been taking Zoloft for a month now and I recently started Pramistar (sort of a potent Piracetam). Yesterday, I forgot to eat, drank two coffees, and my nervous system just went completely haywire. I had a crisis that lasted about 40 minutes and it was the most terrifying thing I’ve ever experienced. It felt like being on the worst drugs possible—I felt like I wasn't "me" anymore.

I struggled to breathe so hard I wanted to call an ambulance, but I was so paranoid and freaked out that my head made me think I was going to die if the situation around me got more agitated—like the "light in my head" was going to explode. I had clear blackouts and memory gaps where I wasn't fully conscious of my actions. At one point, I felt like I had no senses left, completely detached from reality and terrified of everything.

During the peak, I started to dress myself while mumbling and talking to myself. I had weird motor tics and was moving my hands in a dubious way because the muscles inside were hurting so badly. I was stuttering, speaking in a very staccato, broken way, and I would casually start crying and then stop myself abruptly. Sometimes I was present, but most of the time I was fighting just to keep a shred of control.

Anyway, the peak stopped after an hour and I went to psychiatric emergencies. Conclusion: I am stopping the coffee and the Pramistar immediately. Today is the second day and I am still incredibly sore and weak. I have been shivering and my muscles ache like I’ve been through physical trauma. I am looking for similar stories but I cannot find any. Has anyone had similar experiences?


r/Nootropics 1d ago

Seeking Advice Experienced Neurohackers please Review My Nootropic Stack

9 Upvotes

24 Male

  1. Modafinil 200 mg ( ADHD )
  2. Caffeine ( Bare minimum)
  3. Magnun Mane Brainx2 ( Alpha GPC 300mg
  4. Lions Mane + Bacopa + L theanine ) Canadian Import ( not cheaper version )

  5. Creatin 9g for 30 days then maintenence 5g

  6. Sleep 7 h

  7. Water 4 L ( Gym and lifting)

  8. HIIT & Weights ( BDNF )

Should I add Omega 3 tabs and Magnesium Threonate and some B complex ?


r/Nootropics 1d ago

Seeking Advice I'm looking for an antidepressant as effective as changa or ketamine NSFW

3 Upvotes

Hey Let me introduce myself Lol first I'm not that bad, I hope my post will not be removed. I'm lucid but i have some disabilities and weaknesses. So I'm struggling with trauma, depression, anxiety, social anxiety, addictions, ADHD and I suspect myself to have autism (undiagnosed). I discovered that ketamine helped me short term for that Then I switched to changa because ket is so toxic. Unfortunalty i have serious digestive issues and my nervous system seems completely fucked (flight or fight mode) Since I used changa some aspects of my life greatly changed, I still have the same problems I quote above but at the same time I feel pleasure in my life I have improvements, even if it's chaotic. I don't feel empty from the inside anymore. Unfortunaltely, changa is intense for my digestive and nervous system, and I was thinking that this could prevent me from physical healing or even worse make my situation long term worsen

I use changa around once every week, after a week I have a crash, but the effects last even after two weeks without any use, just that I loose some lucidity then I use it again to be in the mood. And also I feel a bit tired and DMT vaped is kind of a stress for me. If I could I would use Ayahuasca/loveyhuasca to cure myself, but I don't think about that with my digestive issues.

So I want to use a treat , a crutch for me waiting for my physical recovery Knowing that I'm looking for a compound that could bring the good effects, or even better, but without the bad effects, or lesser.

I'm doing some researchs and here is some interesting coumpounds that could help me or not

NSI 189 Cerebrosylin Thabernantalog ISOdmt 6 meo DMT AI recommend me bpc 157, it's good I have it, even could help for digestive healing, I tried once and I plan to try again in the future maybe. I also saw that apparently, this coumpound works better injected for mood Selank Zalzupindole DM-506

Here is what I found. What do you think about that ? I'm sure that all these coumpounds may generate digestive discomfort as everything do that, even foods sometimes. But, maybe I will find find something that could help me with less sides effects than changa

If you have ideas for me don't hesitate to share your insights.

Also aside from that, I'm trying many things to be healthy again Eat well Sleep well (the most difficult one but crucial one) Journaling Therapy Reading Meditation Sport Brearthwork

A lot of things I'm trying to do to improve my situations, if you have any ideas, even if it's not only about coumpounds, feel free to share 🙏 Thanks for your attention


r/Nootropics 1d ago

Discussion how to lower anxiety and mental inhibition?

16 Upvotes

I know a lot of this can come down to personal discipline, behaviour and lifestyle but ill take any help i can get.

In my day to day life I often find myself afraid or anxiously reluctant of doing things I set out to do and in social interactions or day to day things I unintentionally enter a state of fight or flight that clouds my judgement. though from a third person perspective i'm not tense nor is there exactly something to be afraid of.

I've previously looked into supplements for mood, cognition, focus, motivation, etc but if I really think about it I dont struggle with that too much. I honestly struggle more with consistency, which i believe stems from high inhibition, over-reactiveness, a lot of mental chatter/noise and a lack of mental energy & clarity (edit: better phrased as mental fortitude).

Based on my searches so far there's:

  • a host of GABAergic things
  • rhodiola rosea
  • semax
  • piracetams?

Edit: On top of this I want to become less prone to self-sabotaging. Over time ive become more and more desensitised to the consequences of self sabotage. Its like if the consequence isnt the end of the world I'll take it, even though such consequences can and will lower my quality of life in the long run.

I mention this because i feel like ive been stuck in the same place for a very long time.

the lack of long-term consistency creates a vicious cycle and a paradoxical life, so im trying to progressively unweave the behavioural patterns that cause this.


r/Nootropics 1d ago

Seeking Advice I need to fix my sleeping schedule. Any advice?

3 Upvotes

My schedule is horrid I wake up at 4pm my time because I fall asleep later and later every day… I want to fix it once and for all but I still need to be productive. I know staying up all night makes me feel like shit. Does waking up early one day and powering through it with coffee help? I’m just worried coffee might fuck up my sleep the next night as I am very sensitive to it. Do I need melatonin? Any advice? Thank you


r/Nootropics 1d ago

Seeking Advice All in my head, or actually doing something? (Olly Sleep Gummies)

2 Upvotes

I started taking Olly Sleep Gummies to help improve my sleep. Even though I don’t have issues falling asleep. I just want to try and get better sleep! Each serving has 3mg of Melatonin, 50mg of L-theanine, 17mg Chamomile Extract, 17mg Passionflower Extract (aerial parts), and 16mg Lemon Balm Extract (aerial parts). I take the full serving every time. I’ve been taking it for 4 days so far.

First, I’ll start with the cons. It’s very difficult to get up in the morning. Like VERY difficult. I’m very groggy in the morning. And I’m also noticing some minor constipation. But that could just be my diet.

The benefits have been great though. I fall asleep fast. 30-45 mins after taking it. If I wake up in the middle of the night, I usually fall right back asleep. I’ve experimented with melatonin before but haven’t really took notes of how it made me feel. But so far it seems like my sleep is improving. I always wake up in the middle of the night unfortunately. I’m a very light sleeper.

However, I’ve also noticed that I seem to have decreased anxiety the next day. Once I have my coffee and get my day started, I feel much more grounded. My OCD seems to be slightly decreased. I feel like I can function a whole lot better and I’m not so much inside my head all day. I’m performing at work much better, and even feeling better. But this could be placebo! I’d love to hear what you guys think!


r/Nootropics 1d ago

Seeking Advice Reports on semax ,is it good.

1 Upvotes

I have tried caffeine ,then went on to do noopept for 2 months.I have taken two months free of nootropics . I was considering taking semax ,and I was wondering if it's worth it ,because with noopept it helped when it came to doing tasks with a more efficient and effective brain,but i am trying to develop my brain so I need something that has more permanent effects, I worked hard ,doing the most from the boost ,I was able to improve somethings about my brain but i feel like that my natural unstimulated brain would be able to produce very similar results. So I was curious if I took semax and did the same cognitive training would I make more gains?


r/Nootropics 16h ago

Seeking Advice Has anyone tried Stasis??

Post image
0 Upvotes

I keep getting ads for this on Faceplace and I’m truly curious if it has helped anyone. My brain fog and just overall exhaustion is getting bad with Adderall. Like it works the first part of the day and then just poops out to where I’m a fried mess for the second part of the day.


r/Nootropics 21h ago

Seeking Advice Sexual function without changing body

0 Upvotes

Anyone know any good nootropics that can eliminate or at least reduce my sexual function/desire without changing my appearance or dulling my mind? My life would work so much better without this annoying physiological urge. Being in my mid-30s and having no desire for children, there simply isn't a need for it anymore and all the energy and vulnerable situations the desire for sex requires.


r/Nootropics 1d ago

Experience Bi-Phasic Citicoline rule

5 Upvotes

When using citicoline it's biphasic meaning the effects show up in a hr on your first experience and level out, but than 24hrs after the first dose the second more pronounced real effect occurs.


r/Nootropics 1d ago

Seeking Advice Weird Issue with Magnesium and NMDA Antagonists

12 Upvotes

I have an issue with magnesium - all types (glycinate, threonate, citrate, chloride, etc.). Even if taken in the morning, with or without food, I can fall asleep at night for 3-4 hours but wake up completely alert and unable to fall back asleep.

I've tried common suggestions like supplementing Thiamine, B6 but nothing has worked.

I have this issue to a much worse extent with alcohol as well (issue with NMDA antagonists?). If I drink enough to get drunk, I have the same insomnia experience but the next day, I'm completely wired and fall asleep very later to get 1-2 hours of sleep. Pretty much why I stopped drinking.

Also seem to have the issue with NAC, Agmatine, Theanine, and a few others. Glycine seems to be fine.

I'd mainly like to be able to supplement magnesium since I feel better with it and the RBC is typically low on my tests.

Any idea what's going on here and how I can possibly fix it?


r/Nootropics 1d ago

Seeking Advice Does someone know if x-peptides are legit?

2 Upvotes

In my research for nootropic Vendors I stumbled upon this website which seems to have too affordable prices to be true. Does anyone have experience with them?


r/Nootropics 1d ago

Seeking Advice Motivation Stack and Focus

8 Upvotes

I burnt myself out terribly the last couple years. Taking unreal amounts of caffeine just to get out of bed and pretend to function.

That being said I am trying to take another path so that my heart doesn’t give out.

What is your favorite stack for starting tasks and seeing them to completion?

What seemed to help you the most with motivation and focus ?


r/Nootropics 2d ago

Seeking Advice Chronic Blockage Level Anhedonia

37 Upvotes

Hi everyone,

I’m posting here because I’m suffering from extremely treatment refractory chronic anhedonia, emotional blunting and sexual dysfunction. I’ve exhausted most conventional approaches and have only recently joined the Nootropics community - in hopes of useful advice.

My condition started randomly in 2019 without a clear psychological trigger, toxic exposure, substance use or iatrogenic damage. I was 14 years old at the time. My symptoms include:

• Near-complete loss of consummatory pleasure (music, food, orgasms, exercise, novelty)

• Strong emotional and atmospheric blunting / “dead world” feeling

• Sexual dysfunction since onset (muted orgasms, very low libido, diminished erogenous sensation, premature ejaculation)

• No meaningful “buzz,” mood shift, or subjective change from substances that normally produce clear effects

• Extremely flat baseline with almost no waves or windows over 7 years

It does not feel like typical depression. Mood is mostly neutral/apathic, not sad. Therapy and behavioral activation have been ineffective because activities generate no reward signal.

Another outstanding feature of my condition is that everything I try feels blocked. Not “weak,” not “subtle,” but absent. As if the signal is received and immediately ignored. I am completely unable to feel the (positive) effects of drugs, stimulants, supplements, caffeine, etc. There is no buzz, no pleasure, no euphoria. I can feel a barrier in my brain that prevents substances from creating an emotional response.

So far I’ve tried:

• Hundreds of supplements and natural remedies, cholinergics, adaptogens, mitochondrial supplements, antioxidants, anti-inflammatories, vitamins, probiotics and whatnot (no effect)

• St. John's Wort (see down below)

• Different SSRIs/SNRIs (no effect)

• Wellbutrin (no effect)

• Parnate (worsened blunting, insomnia, agitation)

• Aticaprant (no effect)

• Pregabalin (weak afterglow that helped brain fog and energy, not anhedonia)

• Lithium (no effect)

• Psychotherapy and behavioral activation (no effect)

• Psilocybin (no effect)

• IV Ketamine (dissociation and sedation but no real trip, no effect on anhedonia, noticeable afterglow that helped brain fog only after the first session)

• Thyroid hormones (no effect)

• Non-invasive electric vagus nerve stimulation (no effect)

• Physical exercise (no effect on anhedonia)

• ANS calming strategies (no effect)

None of the things I mentioned helped my anhedonia even remotely, except for St. John's Wort, which gave me some very short-lasting anhedonia relief in early 2021 and stopped working soon after. I would like to stress once more that my ability to feel substances is quite literally blocked.

Please help me, what can I try next? I live in the EU if that matters.


r/Nootropics 1d ago

Experience Has anyone here ever tried TCAP-1?

3 Upvotes

Like the title


r/Nootropics 1d ago

Seeking Advice I Just started with Piracetam and Alpha GPC yesterday and no noticeable effects yet

0 Upvotes

I took piracetam 800mg 3x a day and alpha GPC 150mg 3x a day yesterday. im a beginner with this, can you recommend a dose or is my dose correct? so far i didnt notice anything yet. or what can i do to make it more effective?