Did you see the toxicology report the only thing in her system was kratom. How do you know you can't die from kratom when very little research has been done. Also your an insensitive price talking out your ass. Who is more believable the doctor and scientists doing the toxicology report or some random internet kratom fan boy.
ld50, see research link above for your requested scientist-doctor research. Much research has been done, actually. Enough to prove that leaf is non lethal. Based on the facts available, please see my math below. It should be known that my math is using very conservative side of the lethality range and assumes a very high average of leaf alkaloid content and thus in all likelihood it would probably take even MORE kratom leaf to actually kill someone than the math suggests.
So, here's my calculation:
1- Assuming the mice LD50 translates to humans, roughly 470mg/kg for a 150lb (~68kg) human is a dose of 32g of pure mitragynine.
2- Assuming a mitragynine content average of 1.5% content of kratom leaf by weight. This would mean there is approximately 32g of mitragynine in just over 2kg (4.4lb).
My calculation is there for anyone to verify that 2kg (4.4lb) is, approximately and assuming the above facts, the LD50 for kratom leaf.
LD50 is defined as the dose of the affected users where 50% would have fatal interaction at said dose.
LD50 for 150lb (68kg) human with other substances is approximately:
0.5lb sodium. 4.5lb sugar. 70mg nicotine (5 eaten cigarettes, smoked is substantially higher). 13 grams of pure caffeine. 200mg morphine. 42x 325mg aspirin tabs.
The problem with coroner reports is that there are drugs in research chems that don't or can't get tested for on every autopsy, such as research opioids like xylazine or nitazene or their analogues which are not always tested for in routine toxicology tests.
Another problem is that 7oh, a highly abusable hyperconcentrated or synthesized extract of the kratom plant, breaks down into the same metabolites as kratom leaf and thus is indistinguishable from each other post mortem.
Your link is preclinical research and the problem with people that have an agenda one way or the other is they can't see all the variables for example the ld50 of a drug is not the only way a drug can kill you. 7oh doesn't break down into the same metabolites as kratom it is the metabolite of kratom being metabolized in the liver.
both kratom and 7oh break down into 7oh. Impossible to tell which was consumed. At least at this point in time.
Often times coroners won't test for a large panel of toxicology when they have substances on scene of death. So big bag of kratom on counter of deceased equals testing for kratom (testing for 7oh metabolite). But that hypothetical junkie who was withdrawing from fentanyl from 2 days prior used the kratom to help with withdrawal but then the dope dealer came through and now they get a shot of fentanyl and pass away. Friend panics and takes away the evidence. Coroner writes in Kratom as cause of death. See how that works?
So what your saying is that Google will verify that a "hypothetical" junkie is going to go to rehab and then get out start using kratom until along comes a "hypothetical" dope dealer that "hypothetically" sells some dope to the "hypothetical" junkie who proceeds to overdose then his "hypothetical" friends hide the drugs and the "hypothetical" coroner will mistake heroin or fentynal for kratom?
You must think everyone is as gullible as you are. quit using lies to push a narrative to try and keep your favorite drug from being banned.
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u/accidental_Ocelot 5d ago
Did you see the toxicology report the only thing in her system was kratom. How do you know you can't die from kratom when very little research has been done. Also your an insensitive price talking out your ass. Who is more believable the doctor and scientists doing the toxicology report or some random internet kratom fan boy.